2,6-Dimethyl-5-ethoxycarbonylpyridine-3-hydrazide and 2,6-dimethylpyridine-3,5-dihydrazide were synthesized by the reaction of diethyl 2,6-dimethylpyridine-3,5-dicarboxylate with hydrazine hydrate in ethanol, then, reacted with substituted benzaldehyde to obtain N-acylhydrazones. At last, a series of new target compounds were formed in the presence of N-bromosuccinimide, which were characterized by ¹H NMR, IR, MS spectra and elemental analyses.

Key words: N-acylhydrazone, pyridine, hydrazide, N-bromosuccinimide, 1,3,4-oxadiazole