Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (04): 574-587. Previous Articles     Next Articles

Review

新型手性亲核催化剂4-二甲胺基吡啶衍生物的研究进展

孙黎,张振锋,谢芳,张万斌*   

  1. (上海交通大学化学化工学院 上海 200240)
  • 收稿日期:2007-06-15 修回日期:2007-08-30 发布日期:2008-04-17
  • 通讯作者: 张万斌

Progress in Chiral 4-Dimethylaminopyridine Derivatives as Novel Nucleophilic Catalysts

SUN Li,ZHANG Zhen-Feng,XIE Fang,ZHANG Wan-Bin*   

  1. (School of Chemistry & Chemical Technology, Shanghai Jiaotong University, Shanghai 200240)
  • Received:2007-06-15 Revised:2007-08-30 Published:2008-04-17
  • Contact: ZHANG Wan-Bin

Chiral 4-dimethylaminopyridine (DMAP) derivatives have been employed in catalytic asymmetric reactions as chiral nucleophilic catalysts with excellent activity and enantioselectivity. At present, study on the applications of chiral DMAP derivatives has been regarded as one of the most remarkable fields in catalytic asymmetric reactions. This review describes the development of chiral DMAP derivatives in recent years.

Key words: chiral DMAP, nucleophilic catalyst, catalytic asymmetric reaction