Iridium-catalyzed asymmetric allylic substitution reaction is one of the most important methods preparing chiral branched compounds. The recent progresses in iridium-catalyzed asymmetric substitution reactions of allylic derivatives are reviewed. Great attention was paid to the influences on this kind of substitution reaction, the structure of ligands and allylic derivatives, the type of nucleophiles, solvents, additives, and so on. Moreover, the enantioselectivity and regioselectivity are also explored in this review.

Key words: iridium-catalysis, asymmetric allylic substitution reaction, nucleophile, recent progress