Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (05): 728-732. Previous Articles     Next Articles

Notes

混合三烃基卤化锡二苯基环己基碘化锡和甲基二环己基氯化锡与巯基乙酸在有机胺存在下的反应产物及生物活性研究

钟桂云*,1,刘清福1,孙丽娟2,谢庆兰2   

  1. (1江门职业技术学院材料技术系 江门 529090)
    (2南开大学元素有机化学国家重点实验室 天津 300071)
  • 收稿日期:2010-08-12 修回日期:2010-10-29 发布日期:2010-12-16
  • 通讯作者: 钟桂云 E-mail:zhongcancan@126.com

Reaction of Ph2CySnI and MeCy2SnCl with HSCH2COOH in the Pres-ence of Organic Amines and Biological Activity for the Reaction Products

Zhong Guiyun*,1 Liu Qingfu1 Sun Li-juan2 Xie Qinglan2   

  1. (1 Department of Material Technology, Jiangmen Polytechnic, Jiangmen 529090)
    (2 Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071)
  • Received:2010-08-12 Revised:2010-10-29 Published:2010-12-16

The reaction of Ph2CySnI and MeCy2SnCl with HSCH2COOH in the presence of organic amine was studied. Two type of products were generated in this reaction. One was no Sn—C cleavage anionic organic tin compound and another was Sn—C cleavage organic tin polymer product. The products have been characterized by elemental analyses, IR, 1H NMR and 13C NMR spectroscopies. The structures of the products were determined. The activity of the products showed that these compounds have a strong anti-tumor activity in vitro.

Key words: five-coordinated tin(IV) complex, ionic organotin, organic tin polymer