The 5-[(1S)-endo]-bornyloxybutyrolactones bearing purine and pyrimidine bases were obtained via the Michael addition of purines or pyrimidines to the epimeric mixture, 5-[(1S)-endo]-bornyloxy-2(5H)- furanones (3a+3b), prepared from the natural abundant chiral auxiliaxy borneol and 5-hydroxy-2(5H)-furanone 2. The synthetic method was studied and the new compounds were identified on the basis of their analytical and spectroscopic, IR, UV, ^1H NMR, ^1^3C NMR, MS data.

Key words: EPIMERISM, FURANONE P, STRUCTURAL ANALYSIS, PHYSICOCHEMICAL CHARACTERISTICS, LACTONE DERIVATIVE, PURINE P, MANNICH REACTION, PYRIMIDINE P, BORNEOLUM SYNTHETICUM NAGI CAMPHORA