Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (03): 437-440. Previous Articles     Next Articles

Reports

乙二胺四乙酸四钠“一锅法”催化合成2-氨基-2-色烯衍生物

陈 路; 李毅群*; 黄旭江 周美云   

  1. (暨南大学化学系 广州 510632)
  • 收稿日期:2008-06-13 修回日期:2008-08-09 发布日期:2009-03-20
  • 通讯作者: 李毅群

One-Pot Synthesis of 2-Amino-2-chromenes Catalyzed by Tetrasodium Ethylenediaminetetraacetate

Chen, Lu ; Li, Yiqun* ; Huang, Xujiang; Zhou, Meiyun   

  1. (Department of Chemistry, Jinan University, Guangzhou 510632)
  • Received:2008-06-13 Revised:2008-08-09 Published:2009-03-20
  • Contact: Li, Yiqun

The synthesis of 2-amino-2-chromenes catalyzed by tetrasodium ethylenediaminetetraacetate (EDTA-4Na) via a one-pot three-component reaction of aromatic aldehyde, malononitrile and 1-naphthol in volume fraction of 95% ethanol has been described. This method offers several advantages such as low cost of the catalyst, mild conditions, good yield, simple experimental and work-up procedure, and reusability of cata-lyst.

Key words: one-pot, 2-amino-2-chromene, tetrasodium ethylenediaminetetraacetate