Chin. J. Org. Chem. ›› 1992, Vol. 12 ›› Issue (3): 253-259. Previous Articles     Next Articles

Original Articles

氯代脱氧蔗糖合成的研究

吴虹桥;王世玉   

  1. 北京大学化学系
  • 发布日期:1992-06-25

Studies on the synthesis of chlorodeoxysucroses

WU HONGQIAO;WANG SHIYU   

  • Published:1992-06-25

Treatment of sucrose alkyl 4,6-orthoacetate hexaacetates I (R = Me, Et) with water or alcohol in the presence of an acid catalyst afforded derivatives of sucrose acetates by selectively blocking specific hydroxyl group in sucrose and acetyl migration. Chlorination of sucrose acetates with Vilsmeier reagent, followed by deesterification afforded chlorodeoxysucroses I (R1 = Cl, OH).

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