Design and Synthesis of Molecular Tweezers Derived from α- Hyodeoxycholic Acid

Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (5): 452-455. Previous Articles Next Articles

α-猪去氧胆酸类分子钳的设计合成

李玲;牟其明;杨祖幸;赵志刚;鄢琦;陈淑华

四川大学化学学院

发布日期:2003-05-25

Design and Synthesis of Molecular Tweezers Derived from α- Hyodeoxycholic Acid

Li Ling;Mu Qiming;Yang Zhuxing;Zhao Zhigang;Yan Qi;Chen Shuhua

Faculty of Shemistry,Sichuan University

Published:2003-05-25

Abstract

A novel type of chiral molecular tweezers has been designed and synthesized by using a-hyodeoxycholic acid as spacer and aromatic compounds as arm. Their structures were characterized by 1H NMR, ffi, MS spectra and elemental analysis. Their recognition properties for aromatic amines and methyl esters of amino acids were investigated. The preliminary results indicate that these chiral molecular tweezers not only recognize neutral molecules, but also show enantio- selectivity for D/L-amino acid methyl esters

Key words: hyodeoxycholic acid;AROMATIC COMPOUNDS;1HNMR;IR;MS;ELEMENTAL ANALYSIS, amino acid methyl esters

CLC Number:

O629

Cite this article

Li Ling;Mu Qiming;Yang Zhuxing;Zhao Zhigang;Yan Qi;Chen Shuhua. Design and Synthesis of Molecular Tweezers Derived from α- Hyodeoxycholic Acid[J]. Chin. J. Org. Chem., 2003, 23(5): 452-455.

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α-猪去氧胆酸类分子钳的设计合成

Design and Synthesis of Molecular Tweezers Derived from α- Hyodeoxycholic Acid

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