Synthesis of New Monocyclic β-Lactams and 4-Thiazolidinones Containing 2-Phenyl-1,2,3-triazolyl

Chin. J. Org. Chem. ›› 2003, Vol. 23 ›› Issue (8): 813-817. Previous Articles Next Articles

含2-苯基-1，2，3-三唑基的单环β-内酰胺及噻唑啉酮衍生物的合成

刘方明;邵玲;张正方;王宝雷;郭群胜;阿布拉江·克依木

新疆大学化学系;南开大学元素有机化学研究所

发布日期:2003-08-25

Synthesis of New Monocyclic β-Lactams and 4-Thiazolidinones Containing 2-Phenyl-1,2,3-triazolyl

Liu Fangming;Shao Ling;Zhang Zhengfang;Wang Baolei;Guo Qunsheng;Ablajan K

Department of Chemistry, Xinjiang University;Natioal Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento- Organic Chemistry, Nankai University

Published:2003-08-25

Abstract

Condensition of arylamine (2) with 2-phenyl-4-foimyl-1,2,3-triazole (1) gave Schiff base 3. The Schiff bases reacted with chloroacetyl chloride and phenoxyacetyl chloride in presence of triethylamine to yield monocylicβ-lactam derivatives 4a~4f and 5a~5f by [2 + 2] cycloaddition, respectively. 4-Thiazolidinones 6a~6f wereobtained by cyclocondensation of Schiff bases 3 and thioglycollic acid. The structures of all new compounds were confirmed by elemental analysis, IR, JH NMR and MS spectra.

Key words: PYRRODIAZOLE P;SCHIFF BASE;CYCLOADDITION REACTION;LACTAM, THIAZOLONE;ELEMENTAL ANALYSIS;IR;1HNMR

CLC Number:

O621

Cite this article

Liu Fangming;Shao Ling;Zhang Zhengfang;Wang Baolei;Guo Qunsheng;Ablajan K. Synthesis of New Monocyclic β-Lactams and 4-Thiazolidinones Containing 2-Phenyl-1,2,3-triazolyl[J]. Chin. J. Org. Chem., 2003, 23(8): 813-817.

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含2-苯基-1，2，3-三唑基的单环β-内酰胺及噻唑啉酮衍生物的合成

Synthesis of New Monocyclic β-Lactams and 4-Thiazolidinones Containing 2-Phenyl-1,2,3-triazolyl

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