Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (08): 1264-1266. Previous Articles     Next Articles

Reports

l’-碘代二茂铁甲醛合成的新方法

郭 建; 庄 顺; 陈松华; 张士博; 袁耀锋*   

  1. (福州大学化学系 福州 350108)
  • 收稿日期:2008-10-07 修回日期:2009-01-04 发布日期:2009-08-30
  • 通讯作者: 袁耀锋

A New Route for the Synthesis of l’-Iodoferrocenecarboxaldehyde

Guo, Jian ; Zhuang, Shun; Chen, Songhua;
Zhang, Shibo; Yuan, Yaofeng*
  

  1. (Department of Chemistry, Fuzhou University, Fuzhou 350108)
  • Received:2008-10-07 Revised:2009-01-04 Published:2009-08-30
  • Contact: Yuan, Yaofeng

Ferrocenecarboxaldehyde is an important intermediate in organic synthetic chemistry. The application of 1’-substituted ferrocenecarboxaldehyde is limited because of the difficulty of synthesis. Due to many reactive sites, 1’-iodoferrocenecarboxaldehyde was widely used in the design and synthesis of functional molecules. The traditional synthetic methods not only require four steps, but also need to use expensive metal-organic reagents. 1’-Iodoferrocenecarboxaldehyde has been prepared from ferrocene through an improved three-step procedure, which features ready availability of the starting materials and simple opera-tion.

Key words: Vilsmeier formylation, l’-iodoferrocenecarbaldehyde, ferrocene derivative