Chin. J. Org. Chem. ›› 1989, Vol. 9 ›› Issue (5): 426-430. Previous Articles     Next Articles

张永敏;胡祖耀   

  1. 杭州大学化学系
  • 发布日期:1989-10-25

(NMCp)2TiCl2-catalyzed reduction of carbonyl compounds by grignard reagent

ZHANG YONGMIN;HU ZUYAO   

  • Published:1989-10-25

Aliphatic, aromatic and a,b-unsatd. ketones were readily reduced to the corresponding secondary alcs. by iso-Pr magnesium bromide in the presence of a catalytic amount of bis(neomenthylcyclopentadienyl)titanium dichloride, while diaryl ketones afforded reduction coupling product pinacols under similar conditions. Aliphatic and aromatic esters were reduced to the corresponding primary alcs. by the Grignard reagent with the same catalyst.

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