Chin. J. Org. Chem. ›› 1995, Vol. 15 ›› Issue (1): 60-63. Previous Articles     Next Articles

Original Articles

二氢(4,5)熏衣草醇的合成

尹鹤群;吴国生;马云飞   

  1. 暨南大学化学系;中国科学院上海有机化学研究所
  • 发布日期:1995-02-25

synthesis of dihydro-4,5-lavandulol

YIN HEQUN;WU GUOSHENG;MA YUNFEI   

  • Published:1995-02-25

A synthetic route of the title compound, a new dihydrogenated derivative of lavendulol, starting with readily available isoanyl from the distillation residue in the ethanol production process with sugarhouse molasses in South China is described. Phase-tramsfer catalytic condensation of isoamyl chloride with acetone gave 6-methyl-2-heptanone in a yield of 43% , which upon methylation and dehydrochlorination led to 2,6-dimethyl-2-heptene. Prins reaction of the alkene with paraformaldehyde in stannic chloride-dichloromethane afforded the final product in a yield of 41.2% . Dihydro (4,5) lavandulol seems to be a mimic with nice but a little milder lavender scent.

Key words: ISOAMYL ALCOHOL, LAVANDULOL, ENVIRONMENTAL PROTECTION

CLC Number: