Synthesis and Insecticidal Evaluation of N,N-DiacylhydrazineDerivatives Containing the Urea Linkage

Abstract

A series of novel N,N-diacylhydrazine derivatives containing the urea linkage were synthesized by the reaction of 2,6-difluorobenzoyl isocyanate (or isocyanatobenzene) with N-tert-butyl-N-substituted benzoylhydrazine or N,N-diacylhydrazines containing amino group in 1,2-dichloroethane under reflux. The results of bioassay showed that some of the title compounds exhibit good larvicidal activities. For ex-ample, the larvicidal activities of derivatives IIa and IIe to Oritental armyworm at the concentration of 0.02% were 95% and 100%, respectively.

Key words: insect growth regulator, larvicidal activity, urea linkage, exuviation, diacylhydrazine

Cite this article

MAO Chun-Hui^1,2,WANG Qing-Min*^,1,OU Xiao-Ming²,HUANG Run-Qiu
CHEN Li,SHANG Jian,BI Fu-Chun^{1. Synthesis and Insecticidal Evaluation of N,N-DiacylhydrazineDerivatives Containing the Urea Linkage[J]. Chin. J. Org. Chem., 2006, 26(01): 60-64.}

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