This review summarizes the recent progress in the research of fluoroporphyrins and its properties. There are two methods for synthesis of the fluoroporphyrins: direct and indirect fluorination. The direct fluorination of porphyrin always involves in using the inorganic fluorination agents to attack the porphyrins while the indirect fluorination of porphyrin employing the fluorinated building block. The fluoroporphyrins are synthesized by the indirect fluorination method more often because the synthesis of porphyrin macrocycle is very complicated.

Key words: indirect fluorination, fluorinated building block, direct fluorination, fluoroporphyrins