Different techniques for fabrication of carbohydrate chips and their research progress are reviewed. The non-covalent immobilization and covalent immobilization methods of carbohydrates on surfaces are the two major fabrication approaches of carbohydrate chips. However, the strategy that carbohydrates are directly attached onto a surface without modification will be the direction of fabrication of carbohydrate chips. The applications of carbohydrate chips are also discussed.

Key words: carbohydrate chip, microarray, biochip, non-covalent immobilization, covalent immobilization