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Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (11): 1728-1743. Previous Articles     Next Articles

Reviews

含氟内酯化合物的合成方法研究进展

熊英a    琚振华a    王晓光a    方向a    吴范宏*,a,b   

  1. (a华东理工大学化学与分子工程学院结构可控先进功能材料及其制备重点实验室 上海 200237) (b中国科学院上海有机化学研究所有机氟化学重点实验室 上海 200032)
  • 收稿日期:2008-11-04 修回日期:2009-02-20 发布日期:2009-04-21
  • 通讯作者: 吴范宏 E-mail:wfh@ecust.edu.cn
  • 基金资助:

    国家级.国家自然科学基金

Progress in the Study on Synthetic Method of Fluorine-containing Lactones

Xiong, Yinga   Ju, Zhenghuaa    Wang, Xiaoguanga    Fang, Xianga   Wu, Fanghong*,a,b   

  1. (a Laboratory for Advanced Material and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237) (b Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2008-11-04 Revised:2009-02-20 Published:2009-04-21

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Lactones are present in a large variety of natural products and biologically active compounds. They are not only useful chiral building blocks for the synthesis of natural products, but also used to synthesis fine chemical products and medicine intermediates. Introduce fluorine or fluorinated groups into lactones can greatly change their biological activity. This article reviews the progress in the study on synthetic method of fluorine-containing lactones.

Key words: fluorine-containing lactone, direct fluorination, building block fluorination