Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (05): 1010-1014.DOI: 10.6023/cjoc201212030 Previous Articles     Next Articles

Articles

单质硒促进的格氏试剂自偶联反应

唐金鹏, 唐渝, 杨骏, 张渊明   

  1. 暨南大学生科院化学系有机化学专业 广州 510632
  • 收稿日期:2012-12-20 修回日期:2013-01-19 发布日期:2013-01-23
  • 通讯作者: 唐渝,tytang@jnu.edu.cn,tzhangym@jnu.edu.cn E-mail:tytang@jnu.edu.cn;tzhangym@jnu.edu.cn
  • 基金资助:

    国家大学生创新(No. 101055920)资助项目.

Selenium-Promoted Homocoupling of Grignard Reagents

Tang Jinpeng, Tang Yu, Yang Jun, Zhang Yuanming   

  1. Department of Chemistry, College of Life Science and Technology, Jinan University, Guangzhou 510632
  • Received:2012-12-20 Revised:2013-01-19 Published:2013-01-23
  • Supported by:

    Project supported by the National University Student Innovative Program (No. 101055920).

The optimized reacting conditions were obtained by exploring the amount of magnesium and selenium, and the influence of catalysts and ligands. 15 homo-coupling aromatic or aliphatic products were obtained in high isolated yields of 65%~92%. A reasonable mechanism of selenium cycling in reaction was proposed based on experimental results.

Key words: Grignard reagent, elemental selenium, homo-coupling