Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (9): 2016-2021.DOI: 10.6023/cjoc201301034 Previous Articles     Next Articles

Notes

三乙胺功能化聚乙二醇双子离子液体催化合成吡喃并[2,3-c]吡唑

王英磊, 罗军, 邢昙昙, 刘祖亮   

  1. 南京理工大学化工学院 南京 210094
  • 收稿日期:2013-01-15 修回日期:2013-03-21 发布日期:2013-05-06
  • 通讯作者: 罗军 E-mail:luojun@njust.edu.cn
  • 基金资助:

    国家自然科学基金(No. 21002050)资助项目

Synthesis of Pyrano[2,3-c]pyrazoles Catalyzed by Poly(ethylene glycol) Bridged Triethylamine Functionalized Dication Ionic Liquid

Wang Yinglei, Luo Jun, Xing Tantan, Liu Zuliang   

  1. School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094
  • Received:2013-01-15 Revised:2013-03-21 Published:2013-05-06
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21002050)

A novel PEG-800 bridged triethylamine functionalized dicationic ionic liquid PEG800-DEIL(Cl) was synthesized and characterized. It was used as an efficient and recyclable catalyst for the synthesis of substituted pyrano[2,3-c]pyrazoles with excellent yields through a one-pot four-component reaction of aromatic aldehydes, malononitrile, ethyl acetoacetate, hydrazine hydrate or phenylhydrazine in water. The environmentally benign protocol was found to be fairly efficient and wide substrate flexibility. The catalytic system could be reused for at least five times without obvious loss of catalytic activity.

Key words: basic ionic liquid, poly(ethylene glycol), pyrano[2,3-c]pyrazole, one-pot, aqueous reaction