Catalytic Asymmetric Hydrosilylation of β,β-Disubstituted Enamides

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张振锋^*()

Zhenfeng Zhang()

Zhenfeng Zhang. Catalytic Asymmetric Hydrosilylation of β,β-Disubstituted Enamides[J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 365-367.

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Figure 1. Chiral α-aminosilane bioactive compounds

Scheme 1. Retrosynthetic analysis of chiral α-aminosilanes

Scheme 2. Efficient synthesis of chiral α-aminosilanes via asymmetric hydrosilylation

Scheme 3. Stereodivergent synthesis of chiral α-aminosilanes

Scheme 4. Catalytic cycle of asymmetric hydrosilylation

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