Reviews

Progress in the Synthesis of 4-Hydroxy-2-pyridone Derivatives

  • Zhao Shengyin ,
  • Huang Jing ,
  • Cheng Jian ,
  • Liu Baoshuo ,
  • Chen Chen
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  • College of Chemistry, Chemical Engineering & Biotechnology, Donghua University, Shanghai 201620

Received date: 2011-09-19

  Revised date: 2011-11-20

  Online published: 2012-04-24

Supported by

Project supported by the Shanghai Municipal Natural Science Foundation of China (No. 10ZR1400700), and the National Natural Science Foundation of China (No. 21072029).

Abstract

4-Hydroxy-2-pyridones are embedded as common structural units of many natural products, which exhibited good or excellent biological activities such as antifungal, antibacterial, and cytototoxic activity and so on. The class of compounds has stimulated a great deal of interest on synthetic chemists due to their structural novelty, molecular diversity, and promising biological activities. In this paper, the recent progress in the synthesis of 4-hydroxy-2-pyridones has been reviewed.

Cite this article

Zhao Shengyin , Huang Jing , Cheng Jian , Liu Baoshuo , Chen Chen . Progress in the Synthesis of 4-Hydroxy-2-pyridone Derivatives[J]. Chinese Journal of Organic Chemistry, 2012 , 32(04) : 651 -660 . DOI: 10.6023/cjoc1109192

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