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Chinese Journal of Organic Chemistry >

2012 , Vol. 32 >Issue 07: 1344 - 1349

DOI: https://doi.org/10.6023/cjoc1110121

Notes

Synthesis and Characterization of Honokiol Bridged Porphyrins as Photosensitizers

  • Huang Qimao ,
  • Wang Siwei ,
  • Deng Pengxing ,
  • Zhou Hong ,
  • Hu Xuelei ,
  • Pan Zhiquan
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  • Key Laboratory for Green Chemical Process of Ministry of Education, Wuhan Institute of Technology, Wuhan 430073

Received date: 2011-10-12

  Revised date: 2012-02-16

  Online published: 2012-03-22

Supported by

Project supported by the National Natural Science Foundation of China (No. 20471045), the Natural Science Foundation of Hubei Province (No. 2008CDB072), the Foundation for Midlife and Youth Excellent Innovation Group of Hubei Province (2008).

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Abstract

Four pairs of porphyrin isomers have been synthesized by reaction of 2-nitrotetraphenylporphyrin and its metallic complexes with 2-naphthol, 1,6-dibromohexane and honokiol respectively, and structurally characterized by UV-vis, 1H NMR, H-H COSY, IR, MS, and elementary analysis. The production of singlet oxygen under radiation was determined with DPBF as the quencher. Their photocleavage ability to pBR322 plasmid DNA has been tested by gel electrophoresis and the interaction with CT DNA was detected by UV-Vis spectroscopy preliminarily.

Key words： porphyrin; honokiol; synthesis; characterization; photosensitivity

Cite this article

Huang Qimao , Wang Siwei , Deng Pengxing , Zhou Hong , Hu Xuelei , Pan Zhiquan . Synthesis and Characterization of Honokiol Bridged Porphyrins as Photosensitizers[J]. Chinese Journal of Organic Chemistry, 2012 , 32(07) : 1344 -1349 . DOI: 10.6023/cjoc1110121

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