Notes

Synthesis and Structure Characterization of Novel 3-Substituted-(thio)chroman-4-one Derivatives

  • Wu Lihuan ,
  • Guo Haifu ,
  • Wang Xinyi ,
  • Wu Ruifen
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  • School of Chemistry and Chemical Engineering, Zhaoqing University, Zhaoqing 526060

Received date: 2011-08-01

  Revised date: 2011-09-18

  Online published: 2012-03-24

Supported by

Project supported by the Scientific and Technological Innovation of Zhaoqing City (No. 2009G12) and the Natural Science Foundation of Guangdong Province (No. 07010338).

Abstract

A series of novel 3-substituted-(thio)chroman-4-one derivatives 3a~3l were synthesized by the condensation of substituted (unsubstituted)-(thio)chromanone with aromatic aldehydes in the presence of sodium hydroxide, via two different methods of conventional solvent method and solvent-free grinding method which has advantages of simple work-up procedure, shorter reaction time, milder conditions and environ-mental friendliness. The structures of the title compounds 3a~3l were characterized by IR, 1H NMR, 13C NMR and MS techniques.

Cite this article

Wu Lihuan , Guo Haifu , Wang Xinyi , Wu Ruifen . Synthesis and Structure Characterization of Novel 3-Substituted-(thio)chroman-4-one Derivatives[J]. Chinese Journal of Organic Chemistry, 2012 , (03) : 608 -611 . DOI: 10.6023/cjoc1108011

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