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Chinese Journal of Organic Chemistry >

2012 , Vol. 32 >Issue 06: 1060 - 1066

DOI: https://doi.org/10.6023/cjoc1201292

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Synthesis and Bioactivities of Novel 1-Phenyl-3-Methyl-5-Aryloxy-1H-Pyrazole-4- Carbaldehyde-O-((2-Chloropyridin-5-yl)methyl)oximes

  • Dai Hong ,
  • Shi Lei ,
  • Zhang Hai-Jun ,
  • Li Yong-Qiang ,
  • Fang Jian-Xin ,
  • Shi Yu-Jun
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  • a College of Chemistry and Chemical Engineering, Nantong University, Nantong 226019;
    b Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071

Received date: 2012-01-29

  Revised date: 2012-03-05

  Online published: 2012-04-11

Supported by

Project supported by the National Natural Science Foundation of China (No. 21102077), the Science and Technology Projects Fund of Nantong City (Nos. K2010016, AS2010005, AS2011011), and the Science Foundation of Nantong University (Nos. 09Z010, 09C001).

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Abstract

Fourteen novel pyrazole oxime ether derivatives containing a 2-chloro-5-methyl pyridyl ring were synthesized by the reaction of 1-phenyl-3-methyl-5-aryloxy-1H-pyrazole-4-carbaldehyde oximes with 2-chloro-5-chloromethyl pyridine. The structures of all new compounds were confirmed by 1H NMR, 13C NMR spectra and elemental analysis. Preliminary bioassay results indicated that some compounds exhibited certain fungicidal and plant growth regulatory activities.

Key words： substituted pyridine; pyrazole oxime; synthesis; bioactivities

Cite this article

Dai Hong , Shi Lei , Zhang Hai-Jun , Li Yong-Qiang , Fang Jian-Xin , Shi Yu-Jun . Synthesis and Bioactivities of Novel 1-Phenyl-3-Methyl-5-Aryloxy-1H-Pyrazole-4- Carbaldehyde-O-((2-Chloropyridin-5-yl)methyl)oximes[J]. Chinese Journal of Organic Chemistry, 2012 , 32(06) : 1060 -1066 . DOI: 10.6023/cjoc1201292

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