Notes

Synthesis of Novel Caffeyl Triterpenic Esters and Their Hepatic Protective Effect

  • Jia Jiong ,
  • Sun Xuehua ,
  • Shao Tengfei ,
  • Jin Shugen ,
  • Gao Yueqiu ,
  • Wang Jianwu
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  • a School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100;
    b Shanghai Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201210

Received date: 2011-08-29

  Revised date: 2011-11-03

  Online published: 2012-04-24

Abstract

Four new caffeyl triterpenic esters were synthesized from natural caffeic acid, glycyrrhetinic acid and oleanolic acid. The structures of all products were characterized by IR, 1H NMR and HRMS techniques. The activities of the compounds to protect liver was tested and compound 9c showed good hepatic protective effect.

Cite this article

Jia Jiong , Sun Xuehua , Shao Tengfei , Jin Shugen , Gao Yueqiu , Wang Jianwu . Synthesis of Novel Caffeyl Triterpenic Esters and Their Hepatic Protective Effect[J]. Chinese Journal of Organic Chemistry, 2012 , 32(04) : 760 -764 . DOI: 10.6023/cjoc1108291

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