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Chinese Journal of Organic Chemistry >

2012 , Vol. 32 >Issue 04: 790 - 793

DOI: https://doi.org/10.6023/cjoc1108181

Notes

A New Tetraphosphine and Its Application in Pd-Catalyzed Suzuki Cross-Coupling Reaction

  • Zhang Yu ,
  • Yi Tao ,
  • Wang Kun ,
  • Fu Haiyan ,
  • Chen Hua ,
  • Li Ruixiang
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  • Key Laboratory of Green Chemistry and Technology of the Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064

Received date: 2011-08-18

  Revised date: 2011-11-21

  Online published: 2012-04-24

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Abstract

A new tetraphosphine, N,N,N',N'-tetra(diphenylphosphinomethyl)-cyclohexane-1,2-diamine (1) has been designed and synthesized from the commercially available cyclohexane-1,2-diamine as starting material. This tetraphosphine in combination with [Pd(η3-C3H5)Cl]2 is a very efficient catalyst for Suzuki cross-coupling reaction. Various aryl- and heteroaryl-chlorides as well as aryl-, heteroaryl-, and alkyl-bromides could be successfully transformed to the desired products in up to 99% yield with 0.1 mol% catalyst loading.

Key words： catalysis; palladium; tetraphosphine; Suzuki cross-coupling; phenylboronic acid

Cite this article

Zhang Yu , Yi Tao , Wang Kun , Fu Haiyan , Chen Hua , Li Ruixiang . A New Tetraphosphine and Its Application in Pd-Catalyzed Suzuki Cross-Coupling Reaction[J]. Chinese Journal of Organic Chemistry, 2012 , 32(04) : 790 -793 . DOI: 10.6023/cjoc1108181

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