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Chinese Journal of Organic Chemistry >

2012 , Vol. 32 >Issue 9: 1653 - 1665

DOI: https://doi.org/10.6023/cjoc1201291

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Transition-Metal-Catalyzed Functionalization of Pyridines

  • Zhang Bin ,
  • Zhou Qizhong ,
  • Chen Rener ,
  • Jiang Huajiang
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  • a College of Pharmacy, Zhejiang University of Technology, Hangzhou 310014;
    b Department of Chemistry, Taizhou University, Taizhou 317000

Received date: 2012-01-29

  Revised date: 2012-04-24

  Online published: 2012-04-06

Supported by

Project supported by the National Natural Science Foundation of China (No.21172166) and the Natural Science Foundation of Zhejiang Province (No.Y4100783)

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Abstract

Pyridines are key backbones of drugs and natural products as well as the key intermediates of medicinal engineering. This paper summarizes transition-metal-catalyzed functionalization of pyridines via C—H activation such as alkylation, alkenylation and arylation etc. as well as their utilities in synthesis of drugs and natural products.

Key words： pyridines; functionalization; alkylation; alkenylation; arylation

Cite this article

Zhang Bin , Zhou Qizhong , Chen Rener , Jiang Huajiang . Transition-Metal-Catalyzed Functionalization of Pyridines[J]. Chinese Journal of Organic Chemistry, 2012 , 32(9) : 1653 -1665 . DOI: 10.6023/cjoc1201291

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