Reviews

Progresses in Synthesis of Benzophenanthridine Alkaloids and Their Derivatives

  • Cheng Pi ,
  • Zeng Jianguo
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  • a Pre-State Key Laboratory for Germplasm Innovation and Utilization of Crop, Hunan Agricultural University, Changsha 410128;
    b National Chinese Medicinal Herbs (Hunan) Technology Center, Hunan Agricultural University, Hunan Agricultural University, Changsha 410128

Received date: 2012-04-06

  Revised date: 2012-05-11

  Online published: 2012-05-01

Supported by

Project supported by the International Scientific and Technological Cooperation Program of State Ministry of Science and Technology (No.2010DFA32810)

Abstract

Benzophenanthridine alkaloids are a small family of natural N-containing compounds that widely distribute in papaveraceous and rutaceous plants and display obvious antitumor and antibacterial activities. In this review, the structure types of natural benzophenanthridine alkaloids are classified based on the particularity of biosynthetic pathway of this group of alkaloids. The synthetic methods of benzophenanthridine alkaloids and related derivatives from 1999 are reviewed with discussion on particularity of each synthetic route.

Cite this article

Cheng Pi , Zeng Jianguo . Progresses in Synthesis of Benzophenanthridine Alkaloids and Their Derivatives[J]. Chinese Journal of Organic Chemistry, 2012 , 32(9) : 1605 -1619 . DOI: 10.6023/cjoc201204008

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