Notes

Synthesis of 1-(2-Amino-3,5-dicyano-4-aryl-4H-pyran-6-yl)guaiazulenes

  • Wang Daolin ,
  • Li ,
  • Di
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  • Key Laboratory of Synthesis & Application of Functional Compound, College of Chemistry, Chemical Engineering & Food Safety, Bohai University, Jinzhou 121003

Received date: 2012-01-06

  Revised date: 2012-05-18

  Online published: 2012-03-01

Supported by

Project supported by the Science and Technology Department of Liaoning Province (No.2011220022)

Abstract

An efficient and convenient method for the one-pot three-component synthesis of 1-(2-amino-3,5-dicyano-4-aryl-4H-pyran-6-yl)guaiazulene derivatives by the condensation of 1-cyanoacetylguaiazulene, aldehydes, and malononitrile in the presence of ammonium acetate has been described. The structures of synthesized compounds were determined by NMR, IR, MS techniques and elemental analysis. This method provides several advantages such as good yield and simple work-up procedure.

Cite this article

Wang Daolin , Li , Di . Synthesis of 1-(2-Amino-3,5-dicyano-4-aryl-4H-pyran-6-yl)guaiazulenes[J]. Chinese Journal of Organic Chemistry, 2012 , 32(9) : 1741 -1745 . DOI: 10.6023/cjoc1201102

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