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Chinese Journal of Organic Chemistry >

2012 , Vol. 32 >Issue 05: 907 - 914

DOI: https://doi.org/10.6023/cjoc1108171

Articles

Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions

  • Guo Shengrong ,
  • Yuan Yanqin ,
  • Zhang Chunniu
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  • Department of Chemistry, Lishui University, Lishui 323000

Received date: 2011-08-17

  Revised date: 2011-12-27

  Online published: 2012-01-10

Supported by

Project supported by the Natural Science Foundation of Zhejiang Province (No. Y407240) and the Key Science Foundation of Lishui University (No. KZ201103).

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Abstract

A highly efficient and simple synthesis of dithiocarbamates is reported in the one-pot reaction of amines, CS2, and alkyl halides without using a catalyst under solvent-free conditions. The mild reaction conditions, high yields, and broad scope of the reaction illustrate the good synthetic utility of this method. The reaction is a highly atom-economic process for production of dithiocarbamates and can be successfully used in large amount for the pharmaceutical or agrochemical industries.

Key words： dithiocarbamates; solvent-free; carbon disulfide; α,β-unsaturated compounds

Cite this article

Guo Shengrong , Yuan Yanqin , Zhang Chunniu . Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions[J]. Chinese Journal of Organic Chemistry, 2012 , 32(05) : 907 -914 . DOI: 10.6023/cjoc1108171

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