Chinese Journal of Organic Chemistry >
Synthesis and Pesticidal Activity of 3-(2-Chloro-4-trifluoromethyl)phenoxy Benzoylhydrazones
Received date: 2012-04-20
Revised date: 2012-05-24
Online published: 2012-06-05
Supported by
Project supported by the National Basic Research Program of China (No. 2010CB126100), and the National Natural Science Foundation of China (Nos. 20372023, 20772042).
A series of new substituted benzaldehyde (or 2-furaldehyde) 3-(2-chloro-4-trifluoromethyl)phenoxy benzoylhy- drazones 4 have been designed and synthesized by the reactions of substituted aldehydes with intermediate 3 in 64%～89% yields. The structures of compounds 4 have been confirmed by 1H NMR, IR, EI-MS and elemental analyses. The structure of 4-chloro-benzaldehyde 3-(2-chloro-4-trifluoromethyl)phenoxy benzoylhydrazone (4f) has been determined by X-ray single crystal diffraction. The results of preliminary bioassay indicated that some compounds possess good fungicidal activities against Rhizoctonia solani and Botrytis cinereapers at a dosage of 50 mg/L and moderate herbicidal activity against the roots of rape and barnyard grass at 100 mg/L.
Key words： benzaldehyde; benzoylhydrazone; fungicidal activity; herbicidal activity
Liu Jianchao , Cui Zeping , He Hongwu . Synthesis and Pesticidal Activity of 3-(2-Chloro-4-trifluoromethyl)phenoxy Benzoylhydrazones[J]. Chinese Journal of Organic Chemistry, 2012 , 32(10) : 1925 -1929 . DOI: 10.6023/cjoc201204022
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