Notes

Studies on Constructing of the Key Intermediate of Eudesmane Sesquiterpenoid Analogues via Diels-Alder Reaction

  • Zhang Yu ,
  • Wang Penghui ,
  • Chu Yong ,
  • Liu Mingming ,
  • Chen Guangyi ,
  • Lu Yinping ,
  • Ye Deyong
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  • Department of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203

Received date: 2011-09-03

  Revised date: 2012-03-08

  Online published: 2012-03-23

Supported by

Project supported by the National Natural Science Foundation of China (No. 30672511) and the National Drug Innovation Program (No. 2009ZX09301-011).

Abstract

The key intermediate of eudesmane sesquiterpenoid analogue 2c was synthesized with high regioselectivity via Diels-Alder reaction from the dienophile 2-methoxyl-6-methyl-1,4-benzoquinone and the diene 1-methoxyl-3-isopropyl-1, 4-butadiene.

Cite this article

Zhang Yu , Wang Penghui , Chu Yong , Liu Mingming , Chen Guangyi , Lu Yinping , Ye Deyong . Studies on Constructing of the Key Intermediate of Eudesmane Sesquiterpenoid Analogues via Diels-Alder Reaction[J]. Chinese Journal of Organic Chemistry, 2012 , 32(07) : 1340 -1343 . DOI: 10.6023/cjoc1109033

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