Chinese Journal of Organic Chemistry >
A Concise Synthesis of Barbigerone and Structural Analogues
Received date: 2012-09-07
Revised date: 2012-10-08
Online published: 2012-10-12
Supported by
Project supported by the National Natural Science Foundation of China (No. 20972152).
A concise and highly efficient protocol for the synthesis of barbigerone and its structural analogues is reported. Resorcinol was converted to the final products via Friedel-Crafts reaction, pyranoid ring formation, aldol reaction, and oxidation-rearrangement-cyclization with 24%～30% overall yields.
Key words： rescocinol; pyranoisoflavones; synthesis; barbigerone; analogues
Yang Youzhe , Wang Chao , Sun Jian . A Concise Synthesis of Barbigerone and Structural Analogues[J]. Chinese Journal of Organic Chemistry, 2013 , 33(01) : 159 -163 . DOI: 10.6023/cjoc201209011
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