Articles

Synthesis of 6-Trimethylsilyl-α-pyrone from 2,6-Bis(trimethylsilyl)- pyran via Mild Aerobic Oxidation

  • Zhou Dejun ,
  • Yuji Matsuya
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  • a School of Physics and Chemistry, Henan Polytechnic University, Jiaozuo 454000, China;
    b Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan

Received date: 2012-09-19

  Revised date: 2012-10-24

  Online published: 2012-11-15

Supported by

Project supported by the Doctoral Fund of Henan Polytechnic University (No. 648536).

Abstract

In this study, an effective and mild method for the synthesis of 6-trimethylsilyl-α-pyrone was successfully developed. 6-Trimethylsilyl-α-pyrone, a very important intermediate in organic synthesis, was mildly synthesized from pyrane derivative via an aerobic oxidation at room temperature, without any solvents and catalysts. Furthermore, the possible mechanism of the reaction was proposed.

Cite this article

Zhou Dejun , Yuji Matsuya . Synthesis of 6-Trimethylsilyl-α-pyrone from 2,6-Bis(trimethylsilyl)- pyran via Mild Aerobic Oxidation[J]. Chinese Journal of Organic Chemistry, 2013 , 33(02) : 375 -377 . DOI: 10.6023/cjoc201209027

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