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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 02: 378 - 382

DOI: https://doi.org/10.6023/cjoc201210031

Articles

Syntheses of 4-(1H)-Quinolones and the Brominated or Methoxy Substituted Derivatives

  • Ma Menglin ,
  • Huang Jianbiao ,
  • Wang Yuliang ,
  • Chen Shuhua ,
  • Chen Hua
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  • a School of Physics and Chemistry, Xihua University, Chengdu 610039;
    b Key Laboratory of Green Chemistry and Technology of Ministry of Education, Faculty of Chemistry, Sichuan University, Chengdu 610064;
    c College of Science, Shanghai University, Shanghai 200444

Received date: 2012-10-17

  Revised date: 2012-11-05

  Online published: 2012-11-15

Supported by

Project supported by the National Natural Science Foundation of China (No. B020601), the Natural Science Foundation of Sichuan Province (No. 07ZA109).

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Abstract

A simple and new synthetic approach to 4-(1H)-quinolones was described. This method was started from ethyl 3,3-diethoxypropanoate and aniline via a synthetic sequence of preparation of key intermediate 3-(phenylimino)propionate and cyclization reaction. The brominated or methoxy substituted derivatives were synthesized by this new method as well.

Key words： 4(1H)quinolones, 3,3-diethoxypropanoate; synthetic method; cyclization

Cite this article

Ma Menglin , Huang Jianbiao , Wang Yuliang , Chen Shuhua , Chen Hua . Syntheses of 4-(1H)-Quinolones and the Brominated or Methoxy Substituted Derivatives[J]. Chinese Journal of Organic Chemistry, 2013 , 33(02) : 378 -382 . DOI: 10.6023/cjoc201210031

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