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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 04: 780 - 791

DOI: https://doi.org/10.6023/cjoc201211023

Reviews

Construction of Metallacycles via Zirconium-Benzyne Complexes and Its Application in Organic Synthesis

  • Mao Kebin ,
  • Fu Xiaoping ,
  • Liu Dan ,
  • Li Shi ,
  • Liu Yuanhong
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  • a Colledge of Chemical Engineering, Shenyang University of Chemical Technology, Shenyang 110142;
    b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032

Received date: 2012-11-13

  Revised date: 2012-11-26

  Online published: 2012-12-07

Supported by

Project supported by the National Natural Science Foundation of China (Nos. 21072208, 21125210, 21121062) and the Major State Basic Research Development Program (973 Program, No. 2011CB808700).

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Abstract

Zirconium-benzyne complex is an important and highly reactive organometallic species. It can react with unsaturated substrates such as alkenes, alkynes, aldehydes, ketones, nitriles etc. to form metallacyles. A large variety of metallacycles can be constructed by modifying the substitution patterns of the substrates, chemical ratio of reactants, different Cp ligands or reaction conditions and so on. These metallacycles are highly useful for further transformations through the reactions with different electrophiles. This review summarizes the synthetic methods of zirconium-benzyne complexes, reactions of zirconium-benzyne complexes with various unsaturated molecules leading to metallacycles, and the applications of these metallacycles in organic chemistry. An outlook of zirconium-benzyne complexes in organic synthesis is also provided at the end of this review.

Key words： zirconium-benzyne; metallacycle; reactivity; coupling reaction

Cite this article

Mao Kebin , Fu Xiaoping , Liu Dan , Li Shi , Liu Yuanhong . Construction of Metallacycles via Zirconium-Benzyne Complexes and Its Application in Organic Synthesis[J]. Chinese Journal of Organic Chemistry, 2013 , 33(04) : 780 -791 . DOI: 10.6023/cjoc201211023

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