Articles

Synthesis and Characterization of A New Rhodamine Fluorescence Molecular Chemosensor for Calcium Ion

  • Su Wenqi ,
  • Tong Jie ,
  • Yang Bingqin
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  • Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry, Northwest University, Xi'an 710069

Received date: 2012-12-04

  Revised date: 2013-01-25

  Online published: 2013-02-05

Supported by

Project supported by the National Natural Science Foundation of China (No. 21172178).

Abstract

The novel rhodamine fluorescent chemosensor was synthesized in five steps from 2-aminophenol and 3-(diethylamino)phenol. It exhibited very strong ?uorescence responses to Ca2+ and had remarkably high selectivity to Ca2+ than other metal ions. When the concentration of Ca2+ was in the range of 2×10-6~5×10-5 mol/L, there was a good linearity between the fluorescence intensity of the chemosensor and the concentration of Ca2+.

Cite this article

Su Wenqi , Tong Jie , Yang Bingqin . Synthesis and Characterization of A New Rhodamine Fluorescence Molecular Chemosensor for Calcium Ion[J]. Chinese Journal of Organic Chemistry, 2013 , 33(05) : 982 -987 . DOI: 10.6023/cjoc201212003

References

[1] Clapham, D. E. Cell 2007, 131, 1047.
[2] Floto, R. A.; Mahautsmith, M. P.; Somasundaram, B. Cell Calcium 1995, 18, 377.
[3] Wojda, U.; Salinska, E.; Kuznicki, J. IUBMB Life 2008, 60, 575.
[4] Pani, B.; Singh, B. B. Cell Mol. Life Sci. 2008, 65, 205.
[5] Keisuke, Y.; Hiroki, A.; Kazuhiko, Y. Opt. Rev. 2005, 12, 415.
[6] Kettlewell, S.; Cabrero, P.; Nicklin, S. A.; T. Dowa, J. A. J. Mol. Cell. Cardiol. 2009, 46, 891.
[7] Harkins, A. B.; Kurebayashi, N.; Baylor, S. M. Biophys. J. 1993, 65, 865.
[8] Gee, K. R.; Archer, E. A.; Lapham, L. A.; Leonard, M. E.; Zhou, Z.-L.; John, B.; Diwu, Z. Bioorg. Med. Chem. Lett. 2000, 10, 1515.
[9] Akwasi, M.; Joseph, P. Y. K.; Roger, Y. T. J. Biol. Chem. 1989, 264, 8171.
[10] Liu, Z.-H.; Li, W.- H.; Shen, P.; Cai, R.-X. Acta Chim. Sinica 2004, 62, 445 (in Chinese).
(刘志洪, 李文化, 沈萍, 蔡汝秀, 化学学报, 2004, 62, 445.)
[11] Pieter, A. O.; Robert, E.; Louis, A. L. Bioconjugate Chem. 2001, 12, 203.
[12] Grzegorz, G.; Martin, P.; Roger, Y. T. J. Biol. Chem. 1989, 260, 3440.
[13] Roger, Y. T. Biochemistry 1980, 19, 2396.
[14] Pieter, A. O.; Robert, E. L.; Louis, A. L. Bioconjugate Chem. 2001, 12, 76.
[15] Emmanuel, R.; Fotini, L.; Artemissia, P. N. Cell Calcium 2006, 39, 3.
[16] Boens, N.; Nesibe, A.; Subhendu, S. S.; Amuri, K.; Georges, J. H. Tetrahedron 2006, 62, 684.
[17] Mako, K.; Kai, J. Anal. Chem. 2010, 82, 6472.
[18] Nikola, B.; Mukulesh, B.; Qin, W.-W.; Bert, M.; Mario, S.; Wim, D.; Noel, B. Org. Biomol. Chem. 2005, 3, 2755.
[19] Yu, C.-W.; Zhang, J.; Li, J.-H.; Liu, P. Microchim. Acta 2011, 174, 247.
[20] Tang, L.-J.; Li, F.-F.; Liu, M.-H.; Raju, N. Spectrochim. Acta, Part A 2011, 78, 1168.
[21] Duong, T. Q.; Jong, S. K. Chem. Rev. 2010, 110, 6280.
[22] Li, J.-B.; Hu, Q.-H.; Zeng, Y.; Yu, X.-L.; Pan, Z.-Q. Prog. Chem. 2012, 24, 823 (in Chinese).
(黎俊波, 胡启辉, 曾阳, 余响林, 潘志权, 化学进展, 2012, 24, 823.)
[23] Zhou, Y.; Wang, F.; Kim, Y.; Kim, S. J.; Yoon, J. Org. Lett. 2009, 11, 4442.
[24] Li, N.; Liu, M.-L.; Yin, W.-T.; Yang, Z.; Li, J.-L.; Shi, Z. Chin. J. Org. Chem. 2011, 31, 39 (in Chinese).
(李娜, 刘美玲, 尹文婷, 杨征, 李剑利, 史真, 有机化学, 2011, 31, 39.)
[25] Du, J.- J.; Fan, J.-L.; Peng, X.- J.; Sun, P. P.; Wang, J.-Y. Org. Lett. 2010, 12, 476.
[26] Sun, W.; Hu, D.-Y.; Wu, Z.-B.; Song, B.-A.; Yang, S. Chin. J. Org. Chem. 2011, 31, 997 (in Chinese).
(孙伟, 胡德禹, 吴志兵, 宋宝安, 杨松, 有机化学, 2011, 31, 997.)
[27] Huang, W.-J.; Wu, W.-H.; Liang, J.-X. Acta Chim. Sinica 2012, 70, 873 (in Chinese).
(黄文君, 吴文辉, 梁嘉香, 化学学报, 2012, 70, 873.)
[28] Yutaka, H.; Rivon, S. K. Theory & Manufacture Dye Chemistry, Gihodo, K. K., Tokyo, 1963, p. 373, p. 788.
[29] Lin, W.-Y.; Yuan, L.; Cao, Z.-M.; Feng, Y.-M.; Song, J.-Z. Angew. Chem. Int. Ed. 2010, 49, 375.
[30] Bert, M.; Mario, S.; Noel, B.; Wim, D. Synthesis 2005, 1838.
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