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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 9: 2016 - 2021

DOI: https://doi.org/10.6023/cjoc201301034

Notes

Synthesis of Pyrano[2,3-c]pyrazoles Catalyzed by Poly(ethylene glycol) Bridged Triethylamine Functionalized Dication Ionic Liquid

  • Wang Yinglei ,
  • Luo Jun ,
  • Xing Tantan ,
  • Liu Zuliang
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  • School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094

Received date: 2013-01-15

  Revised date: 2013-03-21

  Online published: 2013-05-06

Supported by

Project supported by the National Natural Science Foundation of China (No. 21002050)

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Abstract

A novel PEG-800 bridged triethylamine functionalized dicationic ionic liquid PEG800-DEIL(Cl) was synthesized and characterized. It was used as an efficient and recyclable catalyst for the synthesis of substituted pyrano[2,3-c]pyrazoles with excellent yields through a one-pot four-component reaction of aromatic aldehydes, malononitrile, ethyl acetoacetate, hydrazine hydrate or phenylhydrazine in water. The environmentally benign protocol was found to be fairly efficient and wide substrate flexibility. The catalytic system could be reused for at least five times without obvious loss of catalytic activity.

Key words： basic ionic liquid; poly(ethylene glycol); pyrano[2,3-c]pyrazole; one-pot; aqueous reaction

Cite this article

Wang Yinglei , Luo Jun , Xing Tantan , Liu Zuliang . Synthesis of Pyrano[2,3-c]pyrazoles Catalyzed by Poly(ethylene glycol) Bridged Triethylamine Functionalized Dication Ionic Liquid[J]. Chinese Journal of Organic Chemistry, 2013 , 33(9) : 2016 -2021 . DOI: 10.6023/cjoc201301034

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