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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 9: 1994 - 1998

DOI: https://doi.org/10.6023/cjoc201301060

Notes

Synthesis, Crystal Structure and Biological Activity of 3-(2-Chloro-4-trifluoromethylphenoxy)benzoate

  • Peng Hao ,
  • Gao Yujiao ,
  • He Hongwu
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  • Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemitry, Central China Normal University, Wuhan 430079

Received date: 2013-02-25

  Revised date: 2013-05-04

  Online published: 2013-05-08

Supported by

Project supported by the National Basic Research Program of China ((973 Program, No. 2010CB126100)), the National Natural Science Foundation of China (Nos. 21002037, 21172090) and the Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT, No. IRT0953)

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Abstract

A series of new 3-(2-chloro-4-trifluoromethylphenoxy)benzoates (2) have been synthesized by the reactions of substituted phenols with intermediate 3-(2-chloro-4-trifluoromethylphenoxy)benzoyl chloride (1). The structures of compounds have been confirmed by 1H NMR, IR, EI-MS and elemental analyses. The structure of 3-methylphenyl 3-(2-chloro-4-trifluoromethylphenoxy)benzoate (2f) has been determined by single crystal X-ray diffraction. The results of preliminary bioassay indicated that most of title compounds possess a moderate herbicidal activity against dicotyledonous weeds.

Key words： synthesis; diphenyl ether; herbicidal activity

Cite this article

Peng Hao , Gao Yujiao , He Hongwu . Synthesis, Crystal Structure and Biological Activity of 3-(2-Chloro-4-trifluoromethylphenoxy)benzoate[J]. Chinese Journal of Organic Chemistry, 2013 , 33(9) : 1994 -1998 . DOI: 10.6023/cjoc201301060

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