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Chinese Journal of Organic Chemistry >

2013 , Vol. 33 >Issue 06: 1135 - 1143

DOI: https://doi.org/10.6023/cjoc201304001

Articles

Chemical Components of Some Microorganisms Isolated from Specific Habitats and Their Antitumor Activities

  • Li Yaoyao ,
  • Shen Yuemao
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  • Schoole of Pharmaceutical Sciences, Shandong Univercity, Jinan 250012

Received date: 2013-04-01

  Revised date: 2013-05-06

  Online published: 2013-05-08

Supported by

Project supported by the National Natural Science Foundation of China (Nos.81273384, 31028019, 90913024, 30500632, 30430020, 30325044, 30070007).

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Abstract

The discovery of new anti-tumor drugs is a pressing and continual need for human health due to the constant emergence of drug resistant tumor cell lines, and the rising occurrence of cancer.In recent years, researchers are paying more and more attention to the chemical components of microorganisms isolated from specific habitats and their bioactivities.Our group isolated a large number of new bioactive natural products, most with complex structures, from endophytes of medicinal plants and marine microbes.Moreover, the antitumor mechnisms and targets of two classes of compounds were investigated.Our results indicated that these special microbes are of great potential for new bioactive compounds and deserve further explorations.

Key words： endophytes of medicinal plant; marine microbes; natural product; anti-tumor action

Cite this article

Li Yaoyao , Shen Yuemao . Chemical Components of Some Microorganisms Isolated from Specific Habitats and Their Antitumor Activities[J]. Chinese Journal of Organic Chemistry, 2013 , 33(06) : 1135 -1143 . DOI: 10.6023/cjoc201304001

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