Notes

Two New Pimarane-Type Diterpenes from the Metabolites of Xylaria sp. 290

  • Xu Peipei ,
  • You Huaicheng ,
  • Hu Zhiyu ,
  • Li Yaoyao ,
  • Shen Yuemao
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  • a School of Life Sciences, Shandong University, Jinan 250100;
    b School of Life Sciences, Xiamen University, Xiamen 361005;
    c School of Pharmaceutical Sciences, Shandong University, Jinan 250012

Received date: 2013-06-20

  Revised date: 2013-07-09

  Online published: 2013-08-13

Supported by

Project supported by the Major State Basic Research Development Program of China (973 Program, No. 2010CB833802).

Abstract

Two new pimarane-type diterpenes, xylarianes A (1) and B (2), were isolated from the crude extract of the fungus Xylaria sp. 290 along with one known compound of 16-hydroxy-isopimar-7-en-19-oic acid (3). The chemical structures of 13 were elucidated by spectroscopic methods including 1D-NMR and 2D-NMR experiments and HR-ESIMS. The antitumor assay of compounds 13 showed that they have no activities.

Key words: pimarane; diterpene; Xylaria sp.

Cite this article

Xu Peipei , You Huaicheng , Hu Zhiyu , Li Yaoyao , Shen Yuemao . Two New Pimarane-Type Diterpenes from the Metabolites of Xylaria sp. 290[J]. Chinese Journal of Organic Chemistry, 2013 , 33(12) : 2618 -2621 . DOI: 10.6023/cjoc201306031

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