Articles

A One-Pot Tandom Process to Fused 2-Mercaptonicotinamides

  • Zen Chen ,
  • Qu Zhanqing
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  • College of Petroleum Engineering, China University of Petroleum, Qingdao 266555

Received date: 2013-06-30

  Revised date: 2012-08-03

  Online published: 2013-08-21

Abstract

The paper describes a convenient and facile methodology for the synthesis of fused 2-mercaptonicotinamide scaffolds. The synthetic approach is supported by a one-pot tandem reaction process. This process has potential applications in the synthesis of biologically and medicinally relevant compounds.

Cite this article

Zen Chen , Qu Zhanqing . A One-Pot Tandom Process to Fused 2-Mercaptonicotinamides[J]. Chinese Journal of Organic Chemistry, 2013 , 33(12) : 2533 -2537 . DOI: 10.6023/cjoc201306045

References

[1] Maiese, K.; Chong, Z. Z.; Hou, J.; Shang, Y. C. Molecules 2009, 14, 3446.

[2] Li, F.; Chong, Z. Z.; Maiese, K. Curr. Med. Chem. 2006, 14, 883.

[3] Traister, A.; Breitman, I.; Bar-lev, E.; Zvibel, I.; Harel. A.; Halpern, Z.; Oren, R. Scand, J. Gastroenterology 2005, 40, 1226.

[4] Fernandes, C. A.; Fievez, L.; Ucakar, B.; Neyrinck, A. M.; Fillee, C.; Huaux, F.; Delzenne, N. M.; Bureau. F.; Vanbever, R. Am. J. Physiol.: Lung. Cell. Mol. Physiol. 2011, 300, 354.

[5] Chlopicki, S.; Swies, J.; Mogielnicki, A.; Buczko, W.; Bartus, M.; Lomnicka, M.; Adamus, J.; Gebicki, J. Br. J. Pharmacol. 2007, 152, 230.

[6] Liu, D.; Gharavi, R.; Pitta, M.; Gleichmann, M.; Mattson, M. P. NeuroMol. Med. 2009, 11, 28.

[7] Furdas, S. D.; Shekfeh, S.; Bissinger, E. M.; Wagner, J. M.; Schlimme, S.; Valkov, V.; Hendzel, M.; Jung, M.; Sippl, W. Bioorg. Med. Chem. 2011, 19, 3678.

[8] Spencer, J.; Burd, A. P.; Goodwin, C. A.; Merette, S. A. M.; Scully, M. F.; Adatia, T.; Deadman, J. J. Tetrahedron 2002, 58, 1551.

[9] Klimesova, V.; Odlerrova, Z. Cesko-Slov. Farm. 1993, 42, 214.

[10] Chong, Z. Z.; Maiese, K. Br. J. Pharmacol. 2007, 150, 839.

[11] Shang, Y. C.; Chong, Z. Z.; Hou, J.; Maiese, K. Curr. Neurovasc. Res. 2009, 6, 20.

[12] Niu, X. Y.; Yang, B. C.; Li, Y. Q.; Fang, S.; Huang, Z. X.; Xie, C. X. Org. Biomol. Chem. 2013, 11, 4102

[13] Liu, Y. L.; Chu, C. X.; Huang, A. P.; Zhan, C. J.; Ma, Y.; Ma, C. ACS Combinatorial Sci. 2011, 13, 547.

[14] Liu, Y. L.; Ma, Y.; Zhan, C, J.; Huang, A. P.; Ma, C. Synlett 2012, 255.

[15] Shin, K.Y.; Koo, K. D.; Yoo, K. H.; Kang, Y. K.; Park, S. W.; Kim, D. J. Bioorg. Med. Chem. Lett. 2001, 11, 2397.

[16] Fontem, L. A.; Chikoye, D. J. Food, Agric. Environ. 2012, 10, 1572.

[17] McCullough, P. E.; de Barreda, D. G.; Raymer, P. Weed Technol. 2012, 26, 376

[18] Hennigh, D. S.; Al-Khatib, K.; Tuinstra, M. R. Weed Technol. 2010, 24, 411.

[19] Sengar, R. S.; Miller, J. J.; Basu, P. Dalton Trans. 2008, 2569.

[20] Siedlecka, R.; Skarzewski, J. Pol. J. Chem. 2000, 74, 1369.

[21] Correa, A.; Tellitu, I.; Dominguez, E.; SanMartin, R. Org. Lett. 2006, 8, 4811.

[22] Monge, A.; Merino, V. M. J. Heterocycl. Chem. 1985, 22, 1353.

[23] Marat, X. WO 2012080075, 2012 [Chem. Abstr. 2012, 157, 55237].

[24] Tajima, H.; Honda, T.; Kawasima, K.; Sasabuchi, Y.; Yamamoto, M.; Ban, M.; Okamota, K.; Inoue, K.; Inaba, T.; Takeno, Y.; Tsuboi, T.; Tonouchi, A.; Aono, H. Bioorg. Med. Chem. Lett. 2011, 21, 1232.

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