Chinese Journal of Organic Chemistry >
Copper-Catalyzed Trifluoromethylation of Enol Ether
Received date: 2014-03-17
Revised date: 2014-04-10
Online published: 2014-04-16
Supported by
Project supported by the National Natural Science Foundation of China (No. 21202073) and the Fundamental Research Funds for the Central Universities (No. lzujbky-2012-216).
A copper-catalyzed trifluoromethylation of enol ether is developed, which provides a potential strategy for the synthesis of 2-trifluoromethyl enol ether compounds. The reaction is under mild conditions with moderate to good yields. The structures of target compounds were confirmed by NMR, IR, MS, and HRMS.
Key words： copper; fluorine; enol ether; trifluoromethyl
Peng Rui , Yang Binmiao , Chen Zhimin , Xu Li , Wang Shaohua . Copper-Catalyzed Trifluoromethylation of Enol Ether[J]. Chinese Journal of Organic Chemistry, 2014 , 34(5) : 980 -984 . DOI: 10.6023/cjoc201403039
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