Recent Advance of Synthesis and Bioactivities for Steroids with Special Steroidal Nucleus

  • Gan Chunfang ,
  • Sheng Haibing ,
  • Qi Binbin ,
  • Yang Lei ,
  • Zhao Dandan ,
  • Huang Yanmin ,
  • Cui Jianguo
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  • College of Chemistry and Life Science, Guangxi Teachers Education University, Nanning 530001

Received date: 2014-03-18

  Revised date: 2014-04-21

  Online published: 2014-05-07

Supported by

Project supported by the Natural Science Foundation of Guangxi Province (Nos. 2012GXNSFAA053018, 2012GXNSFAA053018) and the Scientific and Technology Research Funding of Guangxi University (No. 200103YB067).

Abstract

By changing the structure of steroidal nucleus, or introducing different functional groups into steroids, some steroidal compounds with various bioactivities might be obtained. In this paper, according to the different types of steroid nucleus structure, combining with the results of our research in steroids with special steroidal nucleus, the advance of synthesis and biological activities for A-nor steroids, B-nor steroids and C-nor-D-homo-steroids is discussed in recent years, and the development trend and application prospect are forecasted.

Cite this article

Gan Chunfang , Sheng Haibing , Qi Binbin , Yang Lei , Zhao Dandan , Huang Yanmin , Cui Jianguo . Recent Advance of Synthesis and Bioactivities for Steroids with Special Steroidal Nucleus[J]. Chinese Journal of Organic Chemistry, 2014 , 34(9) : 1730 -1742 . DOI: 10.6023/cjoc201403040

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