Chinese Journal of Organic Chemistry >
Synthesis of a Carbene Complex and Its Application in Suzuki Reaction
Received date: 2014-08-25
Revised date: 2014-11-04
Online published: 2014-11-13
Supported by
Project supported by the National Natual Science Foundation of China (No. 21402067).
A palladium N-heterocyclic (NHC) complex has been synthesized and successfully developed as an efficient catalyst for the Suzuki coupling reaction of aryl bromides and 4-toluene sulfonic acid aromatic esters with aryl boronic acids. The catalytic reaction proceeded smoothly in dioxane with potassium acetate as the additive at 80 ℃ in an air atmosphere, while the yield of the target product is excellent and the catalyst can be synthesized easily.
Key words： Suzuki coupling reaction; carbene; palladium complex; synthesis
Tang Yan, Yang Feifei, Nie Shipeng, Wang Lin Luo Zhibin, Lu Hongfei . Synthesis of a Carbene Complex and Its Application in Suzuki Reaction[J]. Chinese Journal of Organic Chemistry, 2015 , 35(3) : 705 -711 . DOI: 10.6023/cjoc201408028
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