Chinese Journal of Organic Chemistry >
Total Synthesis of Longistylin A, Longistylin C and Cajanotone
Received date: 2014-10-17
Revised date: 2014-12-05
Online published: 2015-01-09
Supported by
Project supported by the Program for New Century Excellent Talents in University (No.NCET-12-0656), the Innovation Ability Promoting Program in University of Guizhou Province (No.2013-04), the Natural Science Fundation for Youth in Universities of Guizhou Province (No.2014-300).
Natural products longistylin A, longistylin C and cajanotone belong to stilbenes family and exhibit varieties of bioactivities. Using Horner-Wadsworth-Emmons (HWE) and 1,3-sigma rearrangement reactions as key steps, longistylin A and longistylin C have been successfully synthesized in six steps from 3,5-dimethoxy benzoic acid. Besides, using Barbier and 1,3-sigma rearrangement reactions as key steps, cajanotone has been first prepared in eight steps from 3,5-dihydroxy benzoic acid.
Key words： longistylin A; longistylin C; cajanotone; total synthesis
Chen Wenzhang , Wang Cong , Fan Lingling , Wang Jianta , Yue Weizhou , Tang Lei . Total Synthesis of Longistylin A, Longistylin C and Cajanotone[J]. Chinese Journal of Organic Chemistry, 2015 , 35(5) : 1146 -1151 . DOI: 10.6023/cjoc201410024
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