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Chinese Journal of Organic Chemistry >

2015 , Vol. 35 >Issue 11: 2441 - 2444

DOI: https://doi.org/10.6023/cjoc201506001

Notes

New Iridoid Glucoside from Pterocephalus hookeri

  • Zhang Jifa ,
  • Huang Shuai ,
  • Shan Lianhai ,
  • Chen Lin ,
  • Zhang Yi ,
  • Zhou Xianli
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  • a School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031;
    b Key Laboratory of Advanced Technologies of Materials MOE, Southwest Jiaotong University, Chengdu 610031;
    c School of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002;
    d College of Ethnic Medicine, Chengdu University of Traditional Chinese Medicin, Chengdu 611137

Received date: 2015-06-01

  Revised date: 2015-06-25

  Online published: 2015-07-02

Supported by

Project supported by the National Natural Science Foundation of China (Nos. 31171695, 81274193), the Science and Technology Support Programs of Sichuan Province (No. 2013SZ0083), the Basic research on the Application of Sichuan Province, the Fundamental Research Funds for Central Universities (Nos. 2682014RC15, 2682013CX033), and the Small Molecule Natural Medicine Innovation Team (No. 15TD0048).

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Abstract

A new iridoid glucoside, 5-[3-(1-Hydroxyethyl)pyridine],7-loganin ester (1) was isolated from the aerial parts of Pterocephalus hookeri, together with three known compounds, sylvestroside I (2), 8-hydroxypinoresionl-4'-O-β-D-glucoside (3) and 8'-hydroxylpinoresionl-4'-O-β-D-glucoside (4) by silica gel column and Pre-HPLC. Their structures were elucidated on the basis of extensive spectroscopic analysis, including HR-ESIMS, 1D and 2D NMR experiments. Compound 2 was an iridoid glucoside dimer. Compounds 3 and 4 were two tetrahydrofuranoid lignans. All the compounds were isolated from this plant for the first time.

Key words： dipsacaceae; Pterocephalus hookeri; iridoid; tetrahydrofuranoid

Cite this article

Zhang Jifa , Huang Shuai , Shan Lianhai , Chen Lin , Zhang Yi , Zhou Xianli . New Iridoid Glucoside from Pterocephalus hookeri[J]. Chinese Journal of Organic Chemistry, 2015 , 35(11) : 2441 -2444 . DOI: 10.6023/cjoc201506001

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