Chinese Journal of Organic Chemistry >
Acenaphthoimidazole N-Heterocyclic Carbene Palladium ComplexesCatalyzed Cyanation Reactions in Aqueous Accelerated byMicrowave Irradiation
Received date: 2015-06-24
Revised date: 2015-07-09
Online published: 2015-08-17
Supported by
Project supported by the Research Fund of Doctoral Program, Ministry of Education (No. 20130071110032), the Shanghai Leading Academic Discipline Project (B108) and the Department of Chemistry Fudan University.
In the presence of acenaphthoimidazole N-heterocyclic carbene palladium complexes, cyanation of aryl bromides by non-toxic and inexpensive potassium hexacyanoferrate (II) as cyanide source in water has been investigated under microwave conditions. Both electron-donating and electron-withdrawing groups attached to the substrates show unobvious effects on the transformation and produce the corresponding products in good to excellent yields within few minutes, which demonstrate the practicability and environmentally friendliness of the new developed protocol.
Key words： cyanation; N-heterocyclic carbene; microwave assistant; palladium; aqueous phase
Jiang Xiaojun, Shen Yajing, Liu Zelong, Lü Xuliang, Tu Tao . Acenaphthoimidazole N-Heterocyclic Carbene Palladium ComplexesCatalyzed Cyanation Reactions in Aqueous Accelerated byMicrowave Irradiation[J]. Chinese Journal of Organic Chemistry, 2015 , 35(11) : 2389 -2392 . DOI: 10.6023/cjoc201506029
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