Chinese Journal of Organic Chemistry >
Synthesis and Fungicidal Activities of Azaindolyl Thiazoline Compounds
Received date: 2015-07-12
Revised date: 2015-08-19
Online published: 2015-09-17
Supported by
Project supported by the National S&T Pillar Program of China (No. 2011BAE06B02), and the National Natural Science Foundation of China (No. 21172255).
In order to find new agrochemical products with high activities, 20 azaindolyl thiazoline compounds were designed and synthesized, and their structures were identified by spectral methods. At the concentration of 50 mg/L, some of the title compounds showed good fungicidal activities. Among those compounds, the EC50 values of 2a and 2d against Phomopsis asparagi and Pyricularia oryzae Cav are 6.55 and 9.66 mg/L, which are superior or comparable to the control pesticides, then they can serve as the lead compounds for new fungicide discovery.
Key words： azaindolyl; thiazoline; synthesis; fungicidal activity
Ma Hongli , Yan Xiaojing , Xiao Yumei , Yuan Dekai , Zhang Zhenhua , Fu Bin , Yuan Huizhu . Synthesis and Fungicidal Activities of Azaindolyl Thiazoline Compounds[J]. Chinese Journal of Organic Chemistry, 2016 , 36(1) : 158 -164 . DOI: 10.6023/cjoc201507009
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