Chinese Journal of Organic Chemistry >
A Facile Method to Prepare Dihydroflavonol Derivatives
Received date: 2016-05-30
Revised date: 2016-06-25
Online published: 2016-07-15
Supported by
Project supported by the National Natural Science Foundation of China (No.31370378).
A series of dihydroflavonol derivatives were synthesized by the reaction of 2'-hydroxyl chalcone derivatives with H2O2/(CH3CH2)2NH system in anhydrous tetrahydrofuran under low temperature. The influences of reaction temperature, re-action solvents, the kinds and proportion of alkaline additive and oxidants on this reaction were investigated, and the optimal reaction conditions were determined. This method has the advantages of simple operation, mild conditions and convenient post-treatment. Besides, all synthetic products were fully characterized by NMR spectra.
Zhou Zongbao , Wang Hong , Tao Kaiqi , Ye Xiaochuan , Hu Chunling . A Facile Method to Prepare Dihydroflavonol Derivatives[J]. Chinese Journal of Organic Chemistry, 2016 , 36(11) : 2752 -2756 . DOI: 10.6023/cjoc201605044
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