Chinese Journal of Organic Chemistry >
Two New Flavonoids from Kalimeris integrifolia
Received date: 2016-11-18
Revised date: 2016-12-13
Online published: 2017-01-17
Supported by
Project supported by the National Natural Science Foundation of China (No. 81303220), the Natural Sciences Foundation of Anhui Province (No. 11040606M220) and the Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, CAS (No. AB2015001).
Investigation on Kalimeris integrifolia resulted in two compounds by means of various chromatographic techniques (silica gel, Sephadex LH-20, RP-LC and Pre-HPLC). Their structures were determined as 5,8-dihydroxy-2-(3-hydroxy- 4,5-dimethoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one (1) and 5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4-oxo-4H- chromen-8-yl 2-methylbutanoate (2) on the basis of extensive spectroscopic analyses including MS, IR, UV, 1D- and 2D- NMR. Among them, compounds 1 and 2 are two new flavonoids, named as kalinturflavone A (1) and kalinturflavone B (2).
Key words： Kalimeris integrifolia; Asteraceae; chemical constituent; flavonoids
Wang Guokai , Sun Yunpeng , Wang Zheng , Zhang Nan , Wang Gang , Zhou Zhongyu , Liu Jinsong . Two New Flavonoids from Kalimeris integrifolia[J]. Chinese Journal of Organic Chemistry, 2017 , 37(4) : 1016 -1019 . DOI: 10.6023/cjoc201611021
[1] Chinese Flora Editorial Board of Chinese Academy of Sciences Flora of China, Vol. 74, Science Press, Beijing, 1985 (in Chinese).
(中国科学院中国植物志编辑委员, 中国植物志, 第74卷, 科学出版社, 北京, 1985.)
[2] Chinese Herbal Editorial Board Chinese Herbal, Shanghai Science and Technology Press, Shanghai, 1999 (in Chinese).
(国家中医药管理局《中华本草》编委会, 中华本草, 上海科学技术出版社, 上海, 1999.)
[3] Ji, P.; Wang, G. K.;, Liu, J. S.; Luo, Z. H.; Liu, J. K.; Wang, G. Nat. Prod. Res. Dev. 2014, 26, 212 (in Chinese).
(季鹏, 王国凯, 刘劲松, 罗争辉, 刘吉开, 王刚, 天然产物研究与开发, 2014, 26, 212.)
[4] Zhong, W. W.; Liu, J. S.; Zhang, C. E.; Chen A. M.; Xu, Y. S.; Wang G. Guihaia 2012, 32, 261 (in Chinese).
(钟文武, 刘劲松, 张聪佴, 陈爱民, 许应生, 王刚, 广西植物, 2012, 32, 261.)
[5] Wang, G. K.; Liu, J. S.; Zhang, C. E.; Wang, Z.; Cai, B. X.; Wang, G. Chin. Med. Mater. 2015, 38, 82 (in Chinese).
(王国凯, 刘劲松, 张聪佴, 王诤, 蔡百祥, 王刚, 中药材, 2015, 38, 82.)
[6] Liu, J. S.; Wang G.; Wang, G. K.; Yu, B.; Wang, F.; Liu, J. K. Chin. Trad. Pat. Med. 2010, 32, 462 (in Chinese).
(刘劲松, 王国凯, 王刚, 余波, 王飞, 刘吉开, 中成药, 2010, 32, 462.)
[7] Zhang, J.; Shen, P.; Lu, T.; Yu, D.; Li, H.; Yang, G. Z. Acta Chim. Sinica 2011, 69, 383 (in Chinese).
(张骥, 申鹏, 陆涛, 余丹妮, 李卉, 杨国忠, 化学学报, 2011, 69, 383.)
[8] Tchinda, A. T.; Mouokeu, S. R.; Ngono, R. A.; Ebelle, M. R.; Mokale, A. L.; Nono, D. K.; Frédérich, M. Nat. Prod. Res. 2015, 29, 1990.
[9] Bui, M. L.; Grayer, R. J.; Veitch N. C.; Kiteb, G. C.; Trana, H.; Nguyena, Q. K. Biochem. Syst. Ecol. 2004, 32, 943.
[10] Fushiya, S.; Kishi, Y.; Hattori, K.; Batkhuu J.; Takano, F.; Singab, A. N.; Okuyama, T. Planta Med. 1999, 65, 404.
[11] Parmar, V. S.; Bisht, K. S.; Sharma, S. K.; Jain, R.; Taneja, P.; Singh, S.; Simonsen, O.; Boll, P. M. Phytochemistry 1994, 36, 507.
[12] Xu, N. S.; Yang, H. M.; Cui, M.; Song, F. R.; Liu, Z. Q.; Liu, S. Y. Chin. J. Chem. 2012, 30, 1433.
[13] Zhang, Y. L.; Jiang, L. L.; Xiao, T. S.; Li, Y. B. J. Asian. Nat. Prod. Res. 2015, 17, 717.
[14] Maldonado, E.; Toscano, R. A.; Mancera, C.; Tripp, M. T.; Ortega, A. Phytochemistry 1992, 31, 1003.
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